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The following picture depicts a typical deployment of ACE with MQ and transaction hosts:
ACE is used for integrating with transaction hosts like mainframe and mid-range-based applications, among others, and has connectivity nodes for MQ and Mainframe using Cobol copybook.
After the migration, native JMS applications will be unchanged as Solace supports JMS 1.1 specs. Application servers can communicate with Solace either on JMS or using the JCA resource adapter.
Typically, DataPower appliances are hosted in a DMZ, passing traffic to a core network containing another set of DataPower appliances or an MQ Cluster. PubSub+ is a natural choice for MQ replacement in this scenario as it provides a complete datapath eliminating MQ clusters.